AB0305 RELATIONSHIP BETWEEN IMMUNOLOGICAL ASSESSMENT AND PERIODONTAL STATUS IN RHEUMATOID ARTHRITIS

Background Rheumatoid arthritis (RA) and Periodontitis are two chronic inflammatory diseases, which can share similarities such as the patho-physiological progression immune regulation. Objectives The present study aimed to determine link between immunological assessment periodontal status in RA. Methods A cross sectional including RA patients, consulted or were hospitalized Rheumatology department Taher Sfar University Hospital of Mahdia Tunisia, March 2020 February 2021. diagnosis was based on ACR/EULAR 2010 criteria. Oral examination practiced by a trained dentist same hospital. hygiene, teeth (missing teeth) paradental parameters (bleeding index Loe Silness (GI), plaque indexed O’Leary (PI)) determined for each patient, assess oral diseases Results Our included 73 patients with an average age 51.7 years ±11.8 [21-74years]. Sixty-two (93.9 % cases) women, 35 (54.7%) menopausal. Only one patient smoker. Nine (13.6% diabetic. mean duration 11.2 ± 8.4 [10 months-37 years]. factor (RF) positive 31 Patients (57 cases). Anti-citrullinated peptide antibodies (ACPA) 39 (72 %). Antinuclear (ANA) 5 (9.3%). Fifty (80.6%) had radiological impairments 36 (54.5%) specific deformations disease activity score (DAS28-VS) (DAS28-CRP) very high (>5.1) respectively 14 (21.2%) 8 (12%). revealed xerostomia 37 (62.7% Three (4.7% toothless. Gingivitis diagnosed 45 (65.2% cases): localized 13 (31.7%) generalized 28 (68.3%). seen (50.7% Basing bleeding (51.4%) degree 2 11 (15.7%) 3. Supragingival subgingival detected 62 (88.6 %) 60 (88.2 We performed statistical analysis showed that positivity ACPA significantly associated presence gingivitis. RF ANA not abnormalities. Conclusion In addition functional handicap, rheumatoid has impact status, may be related patients. Disclosure Interests None declared